Separation of 221Fr from 225Ac using diglycolamide solid extractants

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F23%3A00360764" target="_blank" >RIV/68407700:21340/23:00360764 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/s10967-022-08571-z" target="_blank" >https://doi.org/10.1007/s10967-022-08571-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10967-022-08571-z" target="_blank" >10.1007/s10967-022-08571-z</a>

Result language
angličtina
Original language name
Separation of 221Fr from 225Ac using diglycolamide solid extractants
Original language description
This work is focused on the separation of a daughter radionuclide 221Fr from medicinal 225Ac to provide a source of pure 221Fr fraction for other studies. To achieve such a goal, diglycolamide extraction agents were immobilized on polymer matrix and tested in extraction chromatography experiments. Particularly experiments with N,N,N´,N´tetrakis2- ethylhexyldiglycolamide in nitric acid medium provided promising results and the material was further studied in column experiments. The chosen conditions of separation provided 221Fr in yields over 65% with 225Ac contamination under 1% in less than 5 min, which is a sufficient proof of concept suitable for further studies.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry

Project
<a href="/en/project/TJ04000129" target="_blank" >TJ04000129: Separation of radionuclides for targeted alpha particle therapy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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