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Ac-225/Bi-213 Generator System Based on α-zirconium Phosphate Ion Exchanger

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F23%3A00369927" target="_blank" >RIV/68407700:21340/23:00369927 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.iaea.org/sites/default/files/23/10/cn-310_bk_of_abstracts_oct.pdf" target="_blank" >https://www.iaea.org/sites/default/files/23/10/cn-310_bk_of_abstracts_oct.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ac-225/Bi-213 Generator System Based on α-zirconium Phosphate Ion Exchanger

  • Original language description

    The capacity study of prepared α-zirconium phosphate monohydrate (α-ZrP) ion exchanger granulated in polyacrylonitrile matrix (70% loading) was carried out with Eu as a homologue of Ac-225 using column model of future high activity generator and a stock solution Eu with Eu-152 of activity 57.2 kBq. The fractions of Eu-152 solution were collected after pumping the stock solution through the column at various times for gamma measurements and further calculations of theoretical sorbent capacity for Ac-225 which was evaluated as 36.7 TBq/g. The model high activity (75 MBq of parent Ac-225) generator with length of bed of 7.5 cm and diameter of 0.4 cm containing α-ZrP (particle size 0.8-1.0 mm) as a stationary phase eluted with mixture of 0.01M diethylenetriaminepentaacetic acid (DTPA) in 0.005M nitric acid provided Bi213 with yields in the range from 80 to 95 % in 2.6 ml of eluate and the contamination by parent Ac-225 was in tens of ppm up to forty days of using with flow rate of 0.33 ml/min.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10402 - Inorganic and nuclear chemistry

Result continuities

  • Project

    <a href="/en/project/TJ04000129" target="_blank" >TJ04000129: Separation of radionuclides for targeted alpha particle therapy</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů