The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F11%3A00192486" target="_blank" >RIV/68407700:21460/11:00192486 - isvavai.cz</a>
Result on the web
<a href="http://imbm.fbmi.cvut.cz/soubory/sbornik.pdf" target="_blank" >http://imbm.fbmi.cvut.cz/soubory/sbornik.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats.
Original language description
Chitosan (CS) is a functional linear polysaccharide, which is prepared by partial N-deacetylation of chitin. Chitooligosaccharides (COS) can be produced by hydrolysis of CS. They exhibit various types of the potent biological activities useful for medical applications and health care. The changes in the bacterial population, followed by the shifts in the produced bacterial metabolites can significantly alter condition in gastrointestinal tract. In this in vivo study we modulated the changes of fecal bacteria population in healthy rats (groups: control, CS and COS) during administration of CS/COS. PCR-DGGE analysis was used to detect possible changes in bacterial population. The phylogenetic tree was also constructed. For the quantification of total andselected bacterial DNA was used real-time PCR analysis. CS/COS changed the composition of microbial ecosystem of gastrointestinal tract of healthy rats.
Czech name
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Czech description
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Project
<a href="/en/project/EE.2.3.20.0092" target="_blank" >EE.2.3.20.0092: BIO-XUV Research Team Advancement at FBME CTU</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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