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Characterization of colonic microbial community in patients with Alzheimer's disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00202757" target="_blank" >RIV/68407700:21460/12:00202757 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of colonic microbial community in patients with Alzheimer's disease

  • Original language description

    Alzheimer's disease is one of the major neurodegenerative diseases; the elderly population is affected (about 50% at age 85 years). Manifested by memory loss, impairedspeech and worsening of orientation change of personality. According to some research on the emergence and development of the involved metabolites produced in the digestive tract, resulting in a hypothesis concerning the proportion of microbial activity in the etiology of this disease. Comparison of faecal microflora composition differences in healthy people and patients should contribude to understanding the etiology and pathogenesis of the disease. Real Time PCR was used to monitor possible changes in the levels of total bacteria and the levels of individual bacterial groups: Bifidobacteria, Clostridium leptum, Enterobacteriaceae, Lactobacillus- Streptococcus-Enterobacter, and Bacteroides- Prevotella. The DGGE profiles revealed the great complexity and specificity of eachtest subjects and changes in the composition of s

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/EE.2.3.20.0092" target="_blank" >EE.2.3.20.0092: BIO-XUV Research Team Advancement at FBME CTU</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Instuments and Methods for Biology and Medicine 2012

  • ISBN

    978-80-01-05119-1

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    39-41

  • Publisher name

    Czech Technical University

  • Place of publication

    Prague

  • Event location

    Kladno

  • Event date

    May 29, 2012

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article