Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00202770" target="_blank" >RIV/68407700:21460/12:00202770 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds
Original language description
Hydrophobic substances (phthalocy anines) tend to aggregate in hydrophilic environment (bloodstream) and as a result they can lose their unique properties (photosensitivity). This can be overcome by encapsulating the substances into a drug delivery carrier, e.g. spheres from a biocompatible and biodegradable polymer. In thispaper polycaprolactone (PCL) spheres were synthetized by electrospraying, a method for preparation of polymeric micro- and nanospheres by high voltage application to a jet of polymersolution. The concentration dependence of PCL solution was investigated in the range of 1 % PCL solution to 10 % PCL solution. The samples were analyzed by scanning electron microscopy (SEM). The 7 % and 8 % PCL solutions seem to be the best concentration for PCL spheres preparation.
Czech name
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Czech description
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Project
<a href="/en/project/EE.2.3.20.0092" target="_blank" >EE.2.3.20.0092: BIO-XUV Research Team Advancement at FBME CTU</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Instuments and Methods for Biology and Medicine 2012
ISBN
978-80-01-05119-1
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
64-67
Publisher name
Czech Technical University
Place of publication
Prague
Event location
Kladno
Event date
May 29, 2012
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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