Interactions of nitrogen?vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F13%3A00207033" target="_blank" >RIV/68407700:21460/13:00207033 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Interactions of nitrogen?vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes
Original language description
This doctoral thesis presents the study of optical properties of nitrogen-vacancy (NV) centers in variously functionalized fluorescent nanodiamond particles (FND). NV center in diamond is a deep laying point defect which is the diamond bandgap, containing nitrogen and a neighboring vacancy. In this thesis we used the very specific properties of these NV centers engineered in diamond to be used as nanoscale sensors operating in cells. High biocompatibility of nanodiamond, variable FND size ranging from ~5 nm, stable luminescence from its NV centers and simple carbon chemistry for biomolecule grafting make FND an attractive alternative to molecular dyes for drug-delivery. This thesis present a principle of a novel method that can be used for remote monitoring of chemical processes in biological environment based on color changes from photo-luminescent (PL) NV centers in FND. It is proposed to drive the NV luminescence chemically, by alternating the surface chemical potential by interact
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.20.0306" target="_blank" >EE2.3.20.0306: Integration of the team for research and development of new principles of nanotechnology in biomedicine for education and medical practice</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů