Distribution of the pressure and tidal volume in multicompartment model of the lung during mechanical ventilation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F14%3A00310147" target="_blank" >RIV/68407700:21460/14:00310147 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1515/bmt-2014-4414" target="_blank" >http://dx.doi.org/10.1515/bmt-2014-4414</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/bmt-2014-4414" target="_blank" >10.1515/bmt-2014-4414</a>

Result language

angličtina

Original language name

Distribution of the pressure and tidal volume in multicompartment model of the lung during mechanical ventilation

Original language description

Introduction Regional changes of mechanical properties of lung tissue can be a cause of lung tissue injury by ventilator known as ventilator induced lung injury. The aim of this paper is to study the intrapulmonary parameters in the model of the respiratory system that was designed according to the morphometrical description of the lungs. Methods The model of respiratory system was designed for this study according to Horsfield morphological description. Central airways were modeled in the SolidWorks programme and printed on the 3D printer Objet 24 Pro (Stratasys, USA). Alveolar space of the model was divided into the five compartments according to the Horsfield model of the lungs. The alveolar space was modeled by glass demijohns. The model was prepared to allow measuring pressures and tidal volumes in each compartment. Model was ventilated by mechanical convention ventilator Avea (CareFusion, USA). The volume of the air was measured by respiratory monitory Florian (hot-wire anemometer). Measure d data were processed by LabVIEW programme. Parabolic resistor was placed into the entry of alveolar space as simulation of airway obstruction and VT and pressure was measured. Results Conducted measurement on the model showed different effect of resistance and compliance upon the distribution of pressure and tidal volume into the compartments. The changed resistance has only small effect upon the delivery of tidal volume whereas the compliance of the compartment significantly affects the tidal volume. Time trend of the pressure is similar in all compartments with different compliance and also the effect of the changed resistance was only slight.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FS - Medical facilities, apparatus and equipment

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Engineering - Biomedizinische Technik

ISSN

0013-5585

e-ISSN

—

Volume of the periodical

59

Issue of the periodical within the volume

s1

Country of publishing house

DE - GERMANY

Number of pages

1

Pages from-to

"S992"-"S992"

UT code for WoS article

000350405700426

EID of the result in the Scopus database

—