Experimental analysis of cellular membrane mechanical properties

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F17%3A00316566" target="_blank" >RIV/68407700:21460/17:00316566 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Experimental analysis of cellular membrane mechanical properties

Original language description

The study of mechanical processes at the cellular level is currently an essential topic. The study of cell-environment interaction can reveal the possibilities of using nanoparticles in biomedicine. The work is focused at creating a methology for measuring of mechanical properties on living cells using atomic force microscopy and force spectroscopy. So far we have been working on inanimate cells in phosphate-buffered saline. We work with mouse fibroblasts labeled CT26.WT from a colon. This work presents the achieved results of the successful first phase of using atomic force microscopy for cell measurements. The measurement method by atomic force microscopy on living cells is necessary for simple and fast acquisition of required information such as nano-hardness and adhesion of a membrane.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů