Utilisation of reactive oxygen species generated by electric discharge in biomedical engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F18%3A00317627" target="_blank" >RIV/68407700:21460/18:00317627 - isvavai.cz</a>
Result on the web
<a href="http://www.dl.begellhouse.com/journals/5a5b4a3d419387fb,530c9c0e78fa67b7,60fa5b987ee94cb2.html" target="_blank" >http://www.dl.begellhouse.com/journals/5a5b4a3d419387fb,530c9c0e78fa67b7,60fa5b987ee94cb2.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1615/PlasmaMed.2018024524" target="_blank" >10.1615/PlasmaMed.2018024524</a>
Alternative languages
Result language
angličtina
Original language name
Utilisation of reactive oxygen species generated by electric discharge in biomedical engineering
Original language description
Discharge Singlet Oxygen Generator 6 (DSOG-6) is a device generating reactive oxygen and nitrogen species (including singlet oxygen, ozone, atomic oxygen, NOx) by a hybrid RF/DC electric discharge. These reactive species are often used in biomedicine. In this work reactions of selected cell cultures (B16, HT29 and HaCat) with DSOG-6-generated particles were observed and analyzed. Cell cultures were exposed to singlet oxygen or reactive oxygen species generated by a hybrid electric discharge for different time periods. After the exposure a microscopic analysis of the cytomorphology of cells was carried out. Furthermore, cell proliferation of B16 cell line was investigated by xCELLigence System. Finally, preliminary results of qPCR from B16 exposed to singlet oxygen are presented. The main goal of this work was to evaluate if singlet oxygen/reactive oxygen species generated by DSOG-6 could be used in biomedical application (concretely in oncology and dermatology) and DSOG-6 could become a new biomedical device. The secondary aim was to observe the dependence of cell lines behavior on exposure parameters (time intervals, particles in discharge, etc.).
Czech name
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Czech description
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Classification
Type
J<sub>ost</sub> - Miscellaneous article in a specialist periodical
CEP classification
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OECD FORD branch
10305 - Fluids and plasma physics (including surface physics)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plasma Medicine
ISSN
1947-5772
e-ISSN
1947-5772
Volume of the periodical
8
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
147-154
UT code for WoS article
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EID of the result in the Scopus database
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