Analysis of Left Ventricular Unloading by Double Lumen Arterial Cannula During ECMO Assessed by Mathematical Modeling

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F19%3A00321937" target="_blank" >RIV/68407700:21460/19:00321937 - isvavai.cz</a>

Result on the web

<a href="https://www.springer.com/gp/book/9789811090349" target="_blank" >https://www.springer.com/gp/book/9789811090349</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-981-10-9035-6_138" target="_blank" >10.1007/978-981-10-9035-6_138</a>

Result language

angličtina

Original language name

Analysis of Left Ventricular Unloading by Double Lumen Arterial Cannula During ECMO Assessed by Mathematical Modeling

Original language description

Extracorporeal membrane oxygenation is increasingly used for the therapy of the cardiogenic shock. However, it has been repeatedly shown that increased afterload associated with extracorporeal membrane oxygenation significantly deteriorates left ventricular performance. A number of approaches suggested how to deal with left ventricular unloading. Each of these methods requires extra interventions, which increase invasiveness of the method and thus does not correspond with current trends in the mini-invasive performance. Therefore, the development of a mini-invasive method of left heart decompression is a significant issue in extracorporeal membrane oxygenation therapy. The study presents an alternative mini-invasive method for the left ventricular unloading during extracorporeal membrane oxygenation. The draft of double lumen arterial cannula for left ventricular unloading during extracorporeal membrane oxygenation was created in AutoCAD software. The Modelica modeling language was used for modeling and simulations. The initial parameter values were derived from measurements on a female swine. Our simulation results indicate that drainage lumen of the presented double lumen arterial cannula for veno-arterial extracorporeal membrane oxygenation is capable of withdrawing 0.374 L/min during extracorporeal blood flow 1 L/min, 0.441 L/min during 2 L/min, 0.481 L/min during 3 L/min, 0.532 L/min during 4 L/min, 0.560 L/min during 5L/min. The double lumen arterial cannula presents an alternative and perspective solution. It is less invasive than the currently used methods for the left ventricle decompression during veno-arterial extracorporeal membrane oxygenation. The double lumen arterial cannula is capable of achieving left ventricle decompression and blood return while requiring only one single puncture.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

World Congress on Medical Physics and Biomedical Engineering 2018 (Vol. 1)

ISBN

978-981-10-9034-9

ISSN

1680-0737

e-ISSN

—

Number of pages

5

Pages from-to

749-753

Publisher name

Springer Nature Singapore Pte Ltd.

Place of publication

—

Event location

Prague

Event date

Jun 3, 2018

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

000450908300138