Hypoxemic and hyperoxemic likelihood in pulse oximetry ranges: NICU observational study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F19%3A00325729" target="_blank" >RIV/68407700:21460/19:00325729 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1136/archdischild-2017-314448" target="_blank" >https://doi.org/10.1136/archdischild-2017-314448</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1136/archdischild-2017-314448" target="_blank" >10.1136/archdischild-2017-314448</a>
Alternative languages
Result language
angličtina
Original language name
Hypoxemic and hyperoxemic likelihood in pulse oximetry ranges: NICU observational study
Original language description
Objective: Describe the likelihood of hypoxemia and hyperoxemia across ranges of oxygen saturation (SpO2), during mechanical ventilation with supplemental oxygenation. Design: Retrospective observational study. Setting: University affiliated tertiary care neonatal intensive care unit. Patients: Two groups of neonates based on postmenstrual age (PMA): <32 weeks (n=104) and >36 weeks (n=709). Main measures: Hypoxemia was defined as a PaO2 <40 mm Hg, hyperoxemia as a PaO2 of >99 mm Hg and normoxemia as a PaO2 of 50-80 mm Hg. Twenty-five per cent was defined as marked likelihood of hypoxemia or hyperoxemia. Results: From these infants, 18 034 SpO2-PaO2 pairs were evaluated of which 10% were preterm. The PMA (median and IQR) of the two groups were: 28 weeks (27-30) and 40 weeks (38-41). With SpO2 levels between 90% and 95%, the likelihoods of hypoxemia and hyperoxemia were low and balanced. With increasing levels of SpO2, the likelihood of hyperoxemia increased. It became marked in the preterm group when SpO2 was 99%-100% (95% CI 29% to 41%) and in the term group with SpO2 levels of 96%-98% (95% CI 29% to 32%). The likelihood of hypoxemia increased as SpO2 decreased. It became marked in both with SpO2 levels of 80%-85% (95% CI 20% to 31%, 24% to 28%, respectively). Conclusions: The likelihood of a PaO2 <40 mm Hg is marked with SpO2 below 86%. The likelihood of a PaO2 >99 mm Hg is marked in term infants with SpO2 above 95% and above 98% in preterm infants. SpO2 levels between 90% and 95% are appropriate targets for term and preterm infants.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of disease in childhood. Fetal and neonatal edition
ISSN
1359-2998
e-ISSN
1468-2052
Volume of the periodical
104
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
"F274"-"F279"
UT code for WoS article
000471815900009
EID of the result in the Scopus database
2-s2.0-85048888530