The Relationship Between the Thickness of cpRNFL in Segments and Intraocular Pressure
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F22%3A00360875" target="_blank" >RIV/68407700:21460/22:00360875 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.2147/OPTH.S388936" target="_blank" >https://doi.org/10.2147/OPTH.S388936</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/OPTH.S388936" target="_blank" >10.2147/OPTH.S388936</a>
Alternative languages
Result language
angličtina
Original language name
The Relationship Between the Thickness of cpRNFL in Segments and Intraocular Pressure
Original language description
Purpose: The aim of this study was to investigate whether the retinal nerve fibre layer (RNFL) in some segments of the optic nerve disc in pathological intraocular pressure is more damaged in eyes without antiglaucoma treatment. Patients and Methods: The cohort consisted of 69 subjects (122 eyes), 32 males (6x one, 26x both eyes) aged 21 to 76 years and 37 females (4x one and 30x both eyes) aged 22 to 75 years, who were measured to have IOP greater than 21 mmHg (21– 36) in routine ambulatory care. Measurements were performed using the Ocular Response Analyser, taking into account corneal hysteresis. RNFL thickness was measured using the Avanti RTVue XR and was assessed in 8 segments (1-IT, 2-TI, 3-TS, 4-ST, 5-SN, 6-NS, 7-NI, 8-IN). The visual field was examined with a fast threshold glaucoma program using the Medmont M700. The overall defect (OD) was evaluated. Pearson’s correlation coefficient r was used to assess the dependence between the selected parameters. Results: The largest peripapillary changes in RNFL were observed in segments 1, 4, 5 and 8. It should be emphasized that segments 1 and 4 have been temporarily shifted. Segments 5 and 8 then corresponded to the upper (at no. 12) and lower (at no. 6) sectors. Conclusion: The most important result of this study is the finding that the greatest changes in the RNFL layer were observed in pathological IOP at segment 5 (r=- 0.3) and 8 (r=- 0.28), at the point where the fibres of the magnocellular retinal ganglion cells enter the retina.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30207 - Ophthalmology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Ophthalmology
ISSN
1177-5483
e-ISSN
1177-5483
Volume of the periodical
2022
Issue of the periodical within the volume
16
Country of publishing house
NZ - NEW ZEALAND
Number of pages
7
Pages from-to
3673-3679
UT code for WoS article
000884743800001
EID of the result in the Scopus database
2-s2.0-85141502849