Suggested Recommendations for Bystanders after Lutetium Therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F24%3A00379209" target="_blank" >RIV/68407700:21460/24:00379209 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Suggested Recommendations for Bystanders after Lutetium Therapy

Original language description

During lutetium therapy, workers caring for the administered patient in the medical facility and other hospitalized patients in the same room or persons accompanying the discharged patient home or sharing a household with him are exposed to a certain external radiation. Between April and September 2023, 13 measurements were taken of persons who came into contact with the applied patients (for some people, the measurements were conducted repeatedly). Monitoring persons such as drivers transporting the applied patient and family members living with the applied patient was carried out using coats on which pairs of TLDs were placed in 29 positions (20 positions on the chest, abdomen and small pelvis, four positions on each upper limb and one position on the back between the shoulder blades). In addition, an electronic dosimeter was placed at the reference point (upper left side of the chest). TLDs were calibrated to show reading in terms of Hp(10). Approximately 20% of the maximum exposure was measured in a location where personal whole-body dosimeters are routinely worn. The maximum exposure in approximately 45% of cases was in the abdominal region, where the dosimeter placement would have an average correction factor value of approximately 1.5 relative to the reference site. If we were to consider other areas (back of the neck, upper chest, sleeve) where the maximum exposure was measured relative to the reference site, the correction factors ranged from 1.1 to 6.8. In one case, casing contamination was detected. This local exposure from the contamination was estimated to be approximately 30 times higher than the exposure at a distance of roughly 25 cm from the contamination site. It is advisable to pay attention to the spatial distribution of radiation for people in close proximity to the patient after lutetium therapy, which can be administered repeatedly (several times a year). Based on the knowledge of the direction of the dominant radiation, it is possible to recommend a suitable geometry of the treating person towards the patient (sufficient distance from the abdominal area, where, in most cases, the highest radiation level was found) or to suggest the use of a suitable correction factor in the event that the person is monitored with a personal dosimeter on the reference place. This paper was partially supported by the project SGS24/072/OHK4/1T/17.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů