Vessel density and retinal nerve fiber layer in pathological intraocular pressure
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00383612" target="_blank" >RIV/68407700:21460/25:00383612 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.31348/2025/16" target="_blank" >https://doi.org/10.31348/2025/16</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.31348/2025/16" target="_blank" >10.31348/2025/16</a>
Alternative languages
Result language
angličtina
Original language name
Vessel density and retinal nerve fiber layer in pathological intraocular pressure
Original language description
AIM: The aim of the study was to determine the correlation between intraocular pressure (IOP) and thickness of the retinal nerve fiber layer (RNFL), and vascular density (VD) in the optic nerve. MATERIAL AND METHODOLOGY: IOP was greater than 21 mmHg (21-36 mmHg) in all eyes and was measured as the result of an average of three measurements with the instrument Ocular Response Analyzer (ORA, Reichert). RNFL and VD thickness (in the papillary region of 4.5 x 4.5 mm) was measured with the instrument Avanti RTVue XR (Optovue). In the case of the VD, the scan area was further separated into individual anatomical segments. In the case of corrected RNFL (RNFLc), the VD value was subtracted from the total RNFL value. The relationship of IOP to VD, RNFL and RNFLc in each peripapillary segment was determined using a Pearson's correlation coefficient. RESULTS: The most significant correlation with IOP was observed for small vessel VD in a full scan (r = -0.48) and VD in the IT segment (r = -0.48). A similar correlation was observed for IOP and RNFL (r = -0.42). No statistically significant correlation was observed for RNFLc. CONCLUSION: We demonstrated that VD values, specifically WI-VDs and peripapillary VDs in the IT segment, are significant markers for the early diagnosis of glaucoma.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30207 - Ophthalmology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Ceska a Slovenska Oftalmologie
ISSN
1211-9059
e-ISSN
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Volume of the periodical
2025
Issue of the periodical within the volume
15
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
1-5
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-105001999302