Septo-Optic Dysplasia Plus with Bilateral Homonymous Hemianopia – Case Report

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00384992" target="_blank" >RIV/68407700:21460/25:00384992 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.2147/IMCRJ.S513192" target="_blank" >https://doi.org/10.2147/IMCRJ.S513192</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/IMCRJ.S513192" target="_blank" >10.2147/IMCRJ.S513192</a>

Result language

angličtina

Original language name

Septo-Optic Dysplasia Plus with Bilateral Homonymous Hemianopia – Case Report

Original language description

Abstract: The paper presents a case report of a man (born1968) who was examined for unusual changes in the visual fields. During the examination in 2020, the right eye had esotropia, the pupillary reaction was correct. The ocular findings on the anterior segment and the ocular media were normal. The papilla of the right eye was temporally paler with c/d=0.5, the left papilla was pale with c/ d=0.6, otherwise the background was normal. IOP: 16/18 mmHg. During the examination, diffuse loss of the nerve fiber layer (50 um, resp. 49 um) was detected using OCT, and similarly low values were also found for vessel density. The visual fields showed left-sided homonymous hemianopia with central sparing, partially extending into the upper right quadrants. Electrophysiological examinations of the retina (pattern electroretinogram) and the entire visual analyzer (pattern visual evoked potential – PVEP) showed bilaterally lower amplitudes. The latencies of the P00 VEP peak were not prolonged. For these changes, a magnetic resonance imaging (MRI) examination of the brain was performed with the finding of agenesis of the corpus callosum, associated trigone of the lateral ventricles on both sides. Malformation of the development of the cerebral cortex temporooccipitally medially on the right, of the nature of plymicrogyria. Heterotopia of gray matter periventricularly occipitally on the right. Bilateral atrophy of the optic nerves and chiasm. In the case report of SOD plus, unusual changes in the visual fields are described – homonymous left-sided hemianopia with central sparing. MRI examination of the brain helped to classify this lesion in the temporo-occipital medial region on the right with polymicrogyria.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30207 - Ophthalmology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Medical Case Reports Journal

ISSN

1179-142X

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

9

Country of publishing house

NZ - NEW ZEALAND

Number of pages

7

Pages from-to

1159-1165

UT code for WoS article

001566749400001

EID of the result in the Scopus database

2-s2.0-105015339118