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Significant Improvement of Biocompatibility of Polypropylene Mesh for Incisional Hernia Repair by Using Poly-?-Caprolactone Nanofibers Functionalized with Thrombocyte-Rich Solution

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21720%2F15%3A00232099" target="_blank" >RIV/68407700:21720/15:00232099 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21460/15:00232099

  • Result on the web

    <a href="http://dx.doi.org/10.2147/IJN.S77816" target="_blank" >http://dx.doi.org/10.2147/IJN.S77816</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2147/IJN.S77816" target="_blank" >10.2147/IJN.S77816</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Significant Improvement of Biocompatibility of Polypropylene Mesh for Incisional Hernia Repair by Using Poly-?-Caprolactone Nanofibers Functionalized with Thrombocyte-Rich Solution

  • Original language description

    Incisional hernia is the most common postoperative complication, affecting up to 20% of patients after abdominal surgery. Insertion of a synthetic surgical mesh has become the standard of care in ventral hernia repair. However, the implementation of a mesh does not reduce the risk of recurrence and the onset of hernia recurrence is only delayed by 2-3 years. Nowadays, more than 100 surgical meshes are available on the market, with polypropylene the most widely used for ventral hernia repair. Nonetheless, the ideal mesh does not exist yet; it still needs to be developed. Polycaprolactone nanofibers appear to be a suitable material for different kinds of cells, including fibroblasts, chondrocytes, and mesenchymal stem cells. The aim of the study reportedhere was to develop a functionalized scaffold for ventral hernia regeneration. We prepared a novel composite scaffold based on a polypropylene surgical mesh functionalized with poly-?-caprolactone (PCL) nanofibers and adhered thrombocyte

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EI - Biotechnology and bionics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Nanomedicine

  • ISSN

    1178-2013

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    April

  • Country of publishing house

    NZ - NEW ZEALAND

  • Number of pages

    12

  • Pages from-to

    2635-2646

  • UT code for WoS article

    000352013200002

  • EID of the result in the Scopus database

    2-s2.0-84928138287