Human Verbal Memory Encoding Is Hierarchically Distributed in a Continuous Processing Stream

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21730%2F19%3A00330953" target="_blank" >RIV/68407700:21730/19:00330953 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1523/ENEURO.0214-18.2018" target="_blank" >https://doi.org/10.1523/ENEURO.0214-18.2018</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1523/ENEURO.0214-18.2018" target="_blank" >10.1523/ENEURO.0214-18.2018</a>

Result language

angličtina

Original language name

Human Verbal Memory Encoding Is Hierarchically Distributed in a Continuous Processing Stream

Original language description

Processing of memory is supported by coordinated activity in a network of sensory, association, and motor brain regions. It remains a major challenge to determine where memory is encoded for later retrieval. Here, we used direct intracranial brain recordings from epilepsy patients performing free recall tasks to determine the temporal pattern and anatomical distribution of verbal memory encoding across the entire human cortex. High gamma frequency activity (65-115 Hz) showed consistent power responses during encoding of subsequently recalled and forgotten words on a subset of electrodes localized in 16 distinct cortical areas activated in the tasks. More of the high gamma power during word encoding, and less power before and after the word presentation, was characteristic of successful recall and observed across multiple brain regions. Latencies of the induced power changes and this subsequent memory effect (SME) between the recalled and forgotten words followed an anatomical sequence from visual to prefrontal cortical areas. Finally, the magnitude of the memory effect was unexpectedly found to be the largest in selected brain regions both at the top and at the bottom of the processing stream. These included the language processing areas of the prefrontal cortex and the early visual areas at the junction of the occipital and temporal lobes. Our results provide evidence for distributed encoding of verbal memory organized along a hierarchical posterior-to-anterior processing stream.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

20601 - Medical engineering

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

eNeuro

ISSN

2373-2822

e-ISSN

2373-2822

Volume of the periodical

6

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

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UT code for WoS article

000461453600010

EID of the result in the Scopus database

2-s2.0-85062622137