Permeability and biocompatibility of Novel hydrogel wound dressings

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F10%3A63509500" target="_blank" >RIV/70883521:28110/10:63509500 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Permeability and biocompatibility of Novel hydrogel wound dressings
Original language description
Hydrogel dressings are being popularized for wound care management because of their softness, tissue compatibility, and ability to enhance wound healing process. PVP-CMC and PVP-CMC-BA hydrogels were prepared using polyvinylpyrrolidone (PVP), sodium-carboxymethylcellulose (CMC), polyethyleneglycol (PEG), agar, glycerine and without/with boric acid (BA). Permeability: water vapor transmission and microbe penetration and biocompatibility: cytotoxicity, skin irritation, and skin sensitization tests of hydrogels were performed. Water vapor transmission ability of hydrogels shows positive response to gas permeability, whereas microbe penetration ability by Staphylococcus aureus and Escherichia coli shows negative penetrability; thus these two hydrogel dressings could be considered as a good barrier against microbes having an excellent oxygen diffusion property. In vitro assay of cytotoxicity was carried out in presence of human immortalized non-tumorigenic keratinocyte cell line (HaCaT), wh
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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