Colloidal polyaniline dispersions: Antibacterial activity, cytotoxicity and neutrophil oxidative burst

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F14%3A43871538" target="_blank" >RIV/70883521:28110/14:43871538 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/14:00428657 RIV/61389013:_____/14:00428657 RIV/70883521:28610/14:43871538
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0927776514000289" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0927776514000289</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.colsurfb.2014.01.027" target="_blank" >10.1016/j.colsurfb.2014.01.027</a>

Result language
angličtina
Original language name
Colloidal polyaniline dispersions: Antibacterial activity, cytotoxicity and neutrophil oxidative burst
Original language description
Polyaniline colloids rank among promising application forms of this conducting polymer. Cytotoxicity, antibacterial activity, and neutrophil oxidative burst tests were performed on cells treated with colloidal polyaniline dispersions. The antibacterial effect of colloidal polyaniline against gram-positive and gram-negative bacteria was most pronounced for Bacillus cereus and Escherichia coli, with a minimum inhibitory concentration of 3500μgmL-1. The data recorded on human keratinocyte (HaCaT) and a mouse embryonic fibroblast (NIH/3T3) cell lines using an MTT assay and flow cytometry indicated a concentration-dependent cytotoxicity of colloid, with the absence of cytotoxic effect at around 150μgmL-1. The neutrophil oxidative burst test then showed that colloidal polyaniline, in concentrations <150μgmL-1, was not able to stimulate the production of reactive oxygen species in neutrophils and whole human blood. However, it worked efficiently as a scavenger of those already formed.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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