Binding properties of novel adamantane-based homotritopic guests

Result code in IS VaVaI
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Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Binding properties of novel adamantane-based homotritopic guests
Original language description
Molecular containers cucurbit[n]urils (CBn) and cyclodextrins (CD) are extensively studied as hosts in supramolecular chemistry due to their ability to form inclusion complexes with derivatives of adamantane, diamantane or ferrocene with outstanding stability. As a part of our ongoing work, we prepared two C3 symmetrical adamantane-based guests G and studied their binding properties towards CB7 and ?-CD in water at 30oC. Using NMR and titration calorimetry, we revealed that guest's binding sites can beeasily occupied by up to three molecules of ?-CD or CB7 to form binary 1:3 aggregates or by all mutual combinations of CB7 and ?-CD units and aggregates G@(CB7,?-CD2) and G@(CB72,?-CD) were detected. Finally, G-bound ?- CD can be rapidly replaced by CB7due to high selectivity of both guests. The ratio of association constants KCB7/K?-CD was calculated from ITC data to be of 4.7.105 and 5.3.103 for trisimidazolium and trisbenzimidazolium guest, respectively. Therefore, we believe that ou
Czech name
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Czech description
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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