Preparation of active antibacterial biomaterials based on sparfloxacin, enrofloxacin, and lomefloxacin deposited on polyethylene

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521357" target="_blank" >RIV/70883521:28110/18:63521357 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/18:63521357
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/app.46174" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/app.46174</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/app.46174" target="_blank" >10.1002/app.46174</a>

Result language
angličtina
Original language name
Preparation of active antibacterial biomaterials based on sparfloxacin, enrofloxacin, and lomefloxacin deposited on polyethylene
Original language description
Bacterial contamination is one of the biggest drawbacks of implanted biomaterials, which may cause nosocomial infection. Avoiding bacterial adhesion onto the biomaterial surface by preparing active antibacterial biomaterials is an accurate solution. In this study, three of the fluoroquinolones: sparfloxacin, enrofloxacin, and lomefloxacin were selected due to their broad bactericidal effect and immobilized onto low-density polyethylene surface at two different pH values (pH 3 and pH 6), after tailoring the surface by plasma treatment followed by grafting of polymer brush of N-allylmethylamine. Surface wettability test and morphological investigations were carried out by water contact angle measurement and scanning electron microscopy analysis, respectively. Chemical characterizations were carried out by Fourier transform infrared spectra and X-ray photoelectron spectroscopy. Antibacterial activity was checked against Staphylococcus aureus and Escherichia coli strains and results revealed that prepared surfaces were more effective against E. coli than S. aureus especially those prepared at pH 6.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project
<a href="/en/project/GA17-05095S" target="_blank" >GA17-05095S: Biomimetic materials based on conducting polymers</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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