Antibacterial polyurethane / hydrophobic carbon quantum dots composites for biomedical applications

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521368" target="_blank" >RIV/70883521:28110/18:63521368 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/18:63521368

Result on the web

<a href="http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf" target="_blank" >http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Antibacterial polyurethane / hydrophobic carbon quantum dots composites for biomedical applications

Original language description

Hydrophobic carbon quantum dots (hCQDs) and newly prepared polyurethane nanocomposites with hCQDs work on the principle of photodynamic therapy. This material is able to produce reactive oxygen species, in this case singlet oxygen, after irradiation with light of appropriate wavelength. Polymer nanocomposites were prepared by simple swell-encapsulation-shrink method from a hydrophobic carbon quantum dots solution with the size of hCQDs of approximately 5 nm. Their antibacterial effect was tested on two bacteria, namely Escherichia coli and Staphylococcus aureus, which are widely spread, for example in hospital facilities. Cytotoxicity of prepared nanocomposites was tested on mouse embryonic fibroblast cell line and on adenocarcinomic human epithelial cell line. Electron paramagnetic resonance and near infrared fluorescence were used for determination of singlet oxygen production. The structure and other properties of the polymer composites were characterized by atomic force microscopy, transmission electron microscopy, X-photoelectron spectroscopy, photoluminescence spectroscopy, Raman spectroscopy, Fourier-transform infrared spectroscopy and others. The polyurethane / hCQDs composite is a financially and time-saving material and it has a wide range of applications. This material can be used as an antibacterial surface with high effectiveness, for example as flooring material, coatings, coated products, wall and window covering, catheters and other applications where antibacterial effect is required, particularly in medical, biomedical applications and in many other types of industrial production.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project

<a href="/en/project/8X17021" target="_blank" >8X17021: Antibacterial polymeric nanocomposites on the base of carbon nanomaterials</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů