Improvement of the mechanical and biological properties of PVA-based scaffolds by the addition of fractionated Kraft Lignin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521663" target="_blank" >RIV/70883521:28110/18:63521663 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/18:63521663
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Improvement of the mechanical and biological properties of PVA-based scaffolds by the addition of fractionated Kraft Lignin
Original language description
Scaffolds based on poly(vinyl alcohol) (PVA) and Kraft lignin were prepared in a variety of reciprocal ratios. The improvement in mechanical properties correlated with the amount of Kraft lignin in PVA matrices. Similarly, the cytotoxicity increased with the increasing concentration of Kraft lignin. However, none of the tested samples showed severe cytotoxicity. The critical property for any scaffold is the ability of cells to ingrow and survive within its internal structure. The ingrowth of cells was tested using bioreactors creating simulated in vivo conditions. In the context of all the mentioned parameters, the most advantageous properties were exhibited by the scaffold containing 99 wt% of PVA and 1 wt% of Kraft lignin. The composites with 1 wt% of Kraft lignin showed sufficient mechanical stability, a lack of cytotoxicity, and mainly the ability to allow cells to ingrow into the scaffold in a rotation bioreactor.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
Result continuities
Project
<a href="/en/project/LO1504" target="_blank" >LO1504: Centre of Polymer Systems Plus</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů