Furcellaran surface deposition and its potential in biomedical applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F22%3A63556759" target="_blank" >RIV/70883521:28110/22:63556759 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28150/22:63556759 RIV/70883521:28610/22:63556759
Result on the web
<a href="https://www.mdpi.com/1422-0067/23/13/7439" target="_blank" >https://www.mdpi.com/1422-0067/23/13/7439</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms23137439" target="_blank" >10.3390/ijms23137439</a>
Alternative languages
Result language
angličtina
Original language name
Furcellaran surface deposition and its potential in biomedical applications
Original language description
Surface coatings of materials by polysaccharide polymers are an acknowledged strategy to modulate interfacial biocompatibility. Polysaccharides from various algal species represent an attractive source of structurally diverse compounds that have found application in the biomedical field. Furcellaran obtained from the red algae Furcellaria lumbricalis is a potential candidate for biomedical applications due to its gelation properties and mechanical strength. In the present study, immobilization of furcellaran onto polyethylene terephthalate surfaces by a multistep approach was studied. In this approach, N-allylmethylamine was grafted onto a functionalized polyethylene terephthalate (PET) surface via air plasma treatment. Furcellaran, as a bioactive agent, was anchored on such substrates. Surface characteristics were measured by means of contact angle measurements, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). Subsequently, samples were subjected to selected cell interaction assays, such as antibacterial activity, anticoagulant activity, fibroblasts and stem cell cytocompatibility, to investigate the Furcellaran potential in biomedical applications. Based on these results, furcellaran-coated PET films showed significantly improved embryonic stem cell (ESC) proliferation compared to the initial untreated material.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20506 - Coating and films
Result continuities
Project
<a href="/en/project/GA20-28732S" target="_blank" >GA20-28732S: Colloidal systems for topical formulations. Pickering emulsions and polymer based colloids.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1661-6596
e-ISSN
1422-0067
Volume of the periodical
23
Issue of the periodical within the volume
13
Country of publishing house
CH - SWITZERLAND
Number of pages
15
Pages from-to
nestrankovano
UT code for WoS article
000823976200001
EID of the result in the Scopus database
2-s2.0-85133286888