Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28120%2F16%3A43874462" target="_blank" >RIV/70883521:28120/16:43874462 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.4149/BLL_2016_028" target="_blank" >http://dx.doi.org/10.4149/BLL_2016_028</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2016_028" target="_blank" >10.4149/BLL_2016_028</a>

Result language

angličtina

Original language name

Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

Original language description

OBJECTIVES: Vitamin D substitution is recommended in patients with inflammatory bowel disease. Specific guidelines are lacking. The aim of this study was to assess the effect of vitamin D supplementation with respect to dosage and patient compliance. METHODS: A prospective cohort study of 167 Crohn disease/ulcerative colitis outpatients. Patients were screened for serum vitamin D (250HD(2+3)) at the end of summer and in late winter. Demographic data, history of vitamin D supplementation were recorded and matched with prescription records. RESULTS: A total of 57 subjects used vitamin D supplementation (mean dose 1104 IU/day). 250HD(2+3) levels were lower (p < 0.001) in winter both in substituted and unsubstituted group, without any differences between groups within the same season. 250HD(2+3) levels did not correlate with the substitution dose. 52.1 % of subjects were fully compliant with substitution. 250HD(2+3) and prevalence of vitamin D deficit in this group were comparable with unsubstituted subjects except a higher prevalence of vitamin D insufficiency (p < 0.02). CONCLUSION: Fixed dosage of 1100 IU/day of vitamin D was insufficient to correct the deficiency. Patient compliance with vitamin D supplementation was low, however this fact did not significantly contribute to the degree of vitamin D deficiency in this dosage (Tab. 3, Fig. 1, Ref. 21). Text in PDF www.elis.sk.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

AE - Management, administration and clerical work

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bratislava Medical Journal-Bratislavske Lekarske Listy

ISSN

0006-9248

e-ISSN

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Volume of the periodical

117

Issue of the periodical within the volume

3

Country of publishing house

SK - SLOVAKIA

Number of pages

4

Pages from-to

148-151

UT code for WoS article

000371851500005

EID of the result in the Scopus database

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