Formulation, antibacterial activity, and cytotoxicity of 1-monoacylglycerol microemulsions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F14%3A43871742" target="_blank" >RIV/70883521:28610/14:43871742 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28110/14:43871742
Result on the web
<a href="http://dx.doi.org/10.1002/ejlt.201300171" target="_blank" >http://dx.doi.org/10.1002/ejlt.201300171</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ejlt.201300171" target="_blank" >10.1002/ejlt.201300171</a>
Alternative languages
Result language
angličtina
Original language name
Formulation, antibacterial activity, and cytotoxicity of 1-monoacylglycerol microemulsions
Original language description
Antibacterial activity of stable 1-monoacylglycerol (1-MAG) microemulsions (MEs) of capric (C10:0), undecanoic (C11:0), lauric (C12:0), and myristic (C14:0) acids against the growth of gram-positive and gram-negative bacteria was tested and their inhibition effect was compared to that of neat 1-MAG. To reveal their behavior with respect to eukaryotic cells, the cytotoxicity on mouse fibroblasts was also determined. The MEs were studied via pseudo-ternary phase diagrams in order to find out the miscibility areas of all components used. The results indicated that at 1-MAG concentrations of 1000?1900 mg/L, an inhibition of gram-negative strains was improved compared to neat 1-MAG and depended on the fatty acid type; however, at lower 1-MAG concentrations,both systems showed comparable effect. The opposite trend was detected on gram-positive bacteria, where 1-MAGs showed better performance compared to corresponding MEs. The best antibacterial activity against both bacterial types was obse
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0111" target="_blank" >ED2.1.00/03.0111: Centre of Polymer Systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European journal of lipid science and technology
ISSN
1438-7697
e-ISSN
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Volume of the periodical
116
Issue of the periodical within the volume
4
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
448-457
UT code for WoS article
000333756000011
EID of the result in the Scopus database
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