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Formulation, antibacterial activity, and cytotoxicity of 1-monoacylglycerol microemulsions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F14%3A43871742" target="_blank" >RIV/70883521:28610/14:43871742 - isvavai.cz</a>

  • Alternative codes found

    RIV/70883521:28110/14:43871742

  • Result on the web

    <a href="http://dx.doi.org/10.1002/ejlt.201300171" target="_blank" >http://dx.doi.org/10.1002/ejlt.201300171</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/ejlt.201300171" target="_blank" >10.1002/ejlt.201300171</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Formulation, antibacterial activity, and cytotoxicity of 1-monoacylglycerol microemulsions

  • Original language description

    Antibacterial activity of stable 1-monoacylglycerol (1-MAG) microemulsions (MEs) of capric (C10:0), undecanoic (C11:0), lauric (C12:0), and myristic (C14:0) acids against the growth of gram-positive and gram-negative bacteria was tested and their inhibition effect was compared to that of neat 1-MAG. To reveal their behavior with respect to eukaryotic cells, the cytotoxicity on mouse fibroblasts was also determined. The MEs were studied via pseudo-ternary phase diagrams in order to find out the miscibility areas of all components used. The results indicated that at 1-MAG concentrations of 1000?1900 mg/L, an inhibition of gram-negative strains was improved compared to neat 1-MAG and depended on the fatty acid type; however, at lower 1-MAG concentrations,both systems showed comparable effect. The opposite trend was detected on gram-positive bacteria, where 1-MAGs showed better performance compared to corresponding MEs. The best antibacterial activity against both bacterial types was obse

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED2.1.00%2F03.0111" target="_blank" >ED2.1.00/03.0111: Centre of Polymer Systems</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European journal of lipid science and technology

  • ISSN

    1438-7697

  • e-ISSN

  • Volume of the periodical

    116

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    448-457

  • UT code for WoS article

    000333756000011

  • EID of the result in the Scopus database