Bacteriostatic activity of fluoroquinolone coatings on polyethylene films

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F15%3A43873014" target="_blank" >RIV/70883521:28610/15:43873014 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007/s00289-015-1388-2/fulltext.html" target="_blank" >http://link.springer.com/article/10.1007/s00289-015-1388-2/fulltext.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00289-015-1388-2" target="_blank" >10.1007/s00289-015-1388-2</a>

Result language
angličtina
Original language name
Bacteriostatic activity of fluoroquinolone coatings on polyethylene films
Original language description
Low-density polyethylene films were surface modified through a three-step procedure to impart antibacterial property. Plasma treatment was followed by allylamine grafting to generate active functionalities on the surface. Three potent antibiotics including norfloxacin, ciprofloxacin and ofloxacin were then separately coated onto the surfaces. Each step of surface modification was well characterized in terms of chemical composition and bioactivity. It was found that the chemical structure of the antibiotic was highly determining in extent of antibiotic immobilization as well as in final biological performance of the modified substrates. An excellent activity against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacterial growth was observed for norfloxacin-coated substrate which corresponded to the highest amount of the antibiotic immobilized. However, almost no activity was seen for ofloxacin-coated surface. This was attributed to the ease of the antibiotic
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JK - Corrosion and material surfaces
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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