An adamantane-based disubstituted binding motif with picomolar dissociation constants for cucurbit[n]urils in water and related quaternary assemblies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F16%3A43874881" target="_blank" >RIV/70883521:28610/16:43874881 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28110/16:43874881
Result on the web
<a href="http://dx.doi.org/10.1039/c6ra23524g" target="_blank" >http://dx.doi.org/10.1039/c6ra23524g</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c6ra23524g" target="_blank" >10.1039/c6ra23524g</a>
Alternative languages
Result language
angličtina
Original language name
An adamantane-based disubstituted binding motif with picomolar dissociation constants for cucurbit[n]urils in water and related quaternary assemblies
Original language description
A non-axial centerpiece based on 1,3-disubstituted adamantane was designed, and three new guests were prepared. In the structure of the heterotritopic guests, the central adamantane site was combined with two terminal butyl or 1-adamantyl sites. The new central binding motif displayed an extraordinarily high affinity towards CB8'(K-a = (5.3 +/- 0.3) x 10(12) M-1 in water) to allow formation of quaternary assemblies with geometries which are dependent on the nature of macrocycles. Based on the individual binding strengths, the replacement of CB7 by CB8 led to inverse arrangements of the quaternary assemblies; i.e., b-CD is capped at the central site by two CB7 units, while the CB8 prefers the central site to be capped with two b-CD units.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RSC Advances: an international journal to further the chemical sciences
ISSN
2046-2069
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
107
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
105146-105153
UT code for WoS article
000388116500026
EID of the result in the Scopus database
2-s2.0-84994515724