The Effect of Antimicrobial Agents on the Stability of Hydrogels

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F16%3A43875547" target="_blank" >RIV/70883521:28610/16:43875547 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The Effect of Antimicrobial Agents on the Stability of Hydrogels
Original language description
This work is focused on the effect of antimicrobial agents on the stability of hydrogels. The aim of the study was the production of new hydrophilic gelling polymer compositions based on acrylic acid copolymer for application in cosmetology and pharmacy, respectively. The effect of the hydrogel modification with bioactive compounds, such as nisin (originating from whey fermentation products) and essential oils of citrus fruit, on physico-chemical and antibacterial properties of the resulting system was investigated. Prepared hydrogels were subjected to accelerated stress test, during which the pH, the viscosity and the concentrate of nisin (by RP-HPLC) was measured. The antimicrobial efficacy test was also carried out. Results showed the addition of nisin decrease pH and viscosity and vice versa the essential oils do not influence these properties. During the stress test the concentration of nisin was decreased similarly in all prepared samples. All tested systems proved significant reduction of microorganisms growth but synergy of nisin and essential oils was found out and it was found to be promising preservative system. ACKNOWLEDGMENTS
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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