Smart biopolymer scaffolds based on hyaluronic acid and carbonyl iron microparticles: 3D printing, magneto-responsive, and cytotoxicity study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F24%3A63581518" target="_blank" >RIV/70883521:28610/24:63581518 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28110/24:63581518
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acsabm.4c00567" target="_blank" >https://pubs.acs.org/doi/10.1021/acsabm.4c00567</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsabm.4c00567" target="_blank" >10.1021/acsabm.4c00567</a>

Result language
angličtina
Original language name
Smart biopolymer scaffolds based on hyaluronic acid and carbonyl iron microparticles: 3D printing, magneto-responsive, and cytotoxicity study
Original language description
This study deals with utilization of the hyaluronic acid (HA) and carbonyl iron (CI) microparticles to fabricate the magneto-responsive hydrogel scaffolds that can provide triggered functionality upon application of an external magnetic field. The various combinations of the HA and CI were investigated from the rheological and viscoelastic point of view to clearly show promising behavior in connection to 3D printing. Furthermore, the swelling capabilities with water diffusion kinetics were also elucidated. Magneto-responsive performance of bulk hydrogels and their noncytotoxic nature were investigated,, and all hydrogels showed cell viability in the range 75-85%. The 3D printing of such developed systems was successful, and fundamental characterization of the scaffolds morphology (SEM and CT) has been presented. The magnetic activity of the final scaffolds was confirmed at a very low magnetic field strength of 140 kA/m, and such a scaffold also provides very good biocompatibility with NIH/3T3 fibroblasts.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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