Occurrence of adverse events following vaccination in patients with allergies: a prospective study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F71009396%3A_____%2F24%3AN0000004" target="_blank" >RIV/71009396:_____/24:N0000004 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/24:A25038YS

Result on the web

<a href="https://cejph.szu.cz/artkey/cjp-202403-0001_occurrence-of-adverse-events-following-vaccination-in-patients-with-allergies-a-prospective-study.php" target="_blank" >https://cejph.szu.cz/artkey/cjp-202403-0001_occurrence-of-adverse-events-following-vaccination-in-patients-with-allergies-a-prospective-study.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21101/cejph.a8170" target="_blank" >10.21101/cejph.a8170</a>

Result language

angličtina

Original language name

Occurrence of adverse events following vaccination in patients with allergies: a prospective study

Original language description

Objectives: Allergic patients may be concerned about more frequent and/or more severe adverse events following vaccination, which may lead to the refusal of vaccines among these patients. The aim of this study is to assess whether allergic patients have more frequent adverse events (AEs) after vaccination than healthy individuals. Methods: Study participants (N = 591) underwent vaccination of their choice at a selected Vaccination and Travel Medicine Centre. At a 10 to 14-day interval, they were contacted for a telephone questionnaire survey on the occurrence of AEs after vaccination. A group of allergic patients (n = 188) and healthy controls (n = 403) were followed in the study. Results: No significant difference was found in the occurrence of AEs between study and control group. Only in redness and swelling, which was more common in allergic patients, but only in a few individuals. All side effects were minor, such as pain at the injection site or fatigue. No participant experienced a serious or life-threatening adverse event. In the studied group, no statistically significant differences were found even in the occurrence of AEs after singular vs. simultaneous administration of vaccines (p = 0.094), nor after vaccination with inactivated vs. attenuated vaccines (p = 0.655), or after vaccination against bacterial vs. viral infections (p = 0.140). Conclusions: Vaccination of allergic patients did not cause more frequent and/or more serious adverse events in our study compared to healthy people. If general contraindications are observed, then vaccination of allergic patients is considered safe.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Central European Journal of Public Health

ISSN

1210-7778

e-ISSN

1803-1048

Volume of the periodical

32

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

147-154

UT code for WoS article

001339995200001

EID of the result in the Scopus database

2-s2.0-85205446865