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The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F12%3A00009764" target="_blank" >RIV/75010330:_____/12:00009764 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.yrtph.2012.06.001" target="_blank" >http://dx.doi.org/10.1016/j.yrtph.2012.06.001</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.yrtph.2012.06.001" target="_blank" >10.1016/j.yrtph.2012.06.001</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - the report of an ECVAM-EFPIA workshop

  • Original language description

    The main objectives of the workshop were: - to present "in use" experience of the pharmaceutical industry with the 3T3 Neutral Red Uptake Phototoxicity Test (3T3 NRU-PT), - to discuss why it differs from the results in the original validation exercise, -to discuss technical issues and consider ways to improve the usability of the 3T3 NRU-PT for (non-topical) pharmaceuticals, e.g., by modifying the threshold of chemical light absorption to trigger photo-toxicological testing, and by modifying technicalaspects of the assay, or adjusting the criteria used to classify a positive response.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FM - Hygiene

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Regulatory toxicology and pharmacology

  • ISSN

    0273-2300

  • e-ISSN

  • Volume of the periodical

    63

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    480-488

  • UT code for WoS article

    000306885800015

  • EID of the result in the Scopus database