The genomic diversification of the whole Acinetobacter genus: origins, mechanisms, and consequences

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F14%3A00010667" target="_blank" >RIV/75010330:_____/14:00010667 - isvavai.cz</a>
Result on the web
<a href="http://gbe.oxfordjournals.org/content/6/10/2866.full" target="_blank" >http://gbe.oxfordjournals.org/content/6/10/2866.full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/gbe/evu225" target="_blank" >10.1093/gbe/evu225</a>

Result language
angličtina
Original language name
The genomic diversification of the whole Acinetobacter genus: origins, mechanisms, and consequences
Original language description
Bacterial genomics has greatly expanded our understanding of microdiversification patterns within a species, but analyses at higher taxonomical levels are necessary to understand and predict the independent rise of pathogens in a genus. We have sampled,sequenced, and assessed the diversity of genomes of validly named and tentative species of the Acinetobacter genus, a clade including major nosocomial pathogens and biotechnologically important species. We inferred a robust global phylogeny and delimitedseveral new putative species. The genus is very ancient and extremely diverse: Genomes of highly divergent species share more orthologs than certain strains within a species. We systematically characterized elements and mechanisms driving genome diversification, such as conjugative elements, insertion sequences, and natural transformation. We found many error-prone polymerases that may play a role in resistance to toxins, antibiotics, and in the generation of genetic variation. Surprisi
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)