Radiotherapy management of brain metastases using conventional linear accelerator

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F16%3A00011651" target="_blank" >RIV/75010330:_____/16:00011651 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/16:33160458

Result on the web

<a href="http://biomed.papers.upol.cz/pdfs/bio/2016/03/12.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2016/03/12.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2016.043" target="_blank" >10.5507/bp.2016.043</a>

Result language

angličtina

Original language name

Radiotherapy management of brain metastases using conventional linear accelerator

Original language description

Background and Aims. As treatments for primary cancers continue to improve life expectancy, unfortunately, brain metastases also appear to be constantly increasing and life expectancy for patients with brain metastases is low. Longer survival and improved quality of life may be achieved using localised radiological and surgical approaches in addition to low dose corticosteroids. Stereotactic brain radiotherapy is one rapidly evolving localized radiation treatment. This article describes our experience with stereotactic radiotherapy using a linear accelerator. Methods. We reviewed patients treated with stereotactic radiotherapy, from the time of its introduction into daily practice in our Department of Oncology in 2014. We collected the data on patient treatment and predicted survival based on prognostic indices and actual patient outcome. Results. A total of 10 patients were treated by stereotactic radiotherapy, in one case in combination with whole brain radiotherapy and hippocampal sparing. There was no significant treatment related toxicity during the treatment or follow-up and due to the small number of fractions, the overall tolerance of the treatment was excellent. The patient intrafractional movement in all cases was under 1 mm suggesting that 1 mm margin around the CTV to create the PTVis sufficient and also that patient immobilization using the thermoplastic mask compared with invasive techniques, is feasible. We also found that prognostic indices such as the Graded Prognostic Assessment provide accurate predictions of patient survival. Conclusions. Based on our current evidence, patients with brain metastases fit enough, should be considered for stereotactic radiotherapy treatment.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers of the Medical Faculty of Palacký University, Olomouc, Czech Republic

ISSN

1213-8118

e-ISSN

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Volume of the periodical

160

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

412-416

UT code for WoS article

000392808100012

EID of the result in the Scopus database

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