Differences in cognitive functions between cytomegalovirus-infected and cytomegalovirus-free university students: a case control study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F18%3A00012173" target="_blank" >RIV/75010330:_____/18:00012173 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/18:10378764

Result on the web

<a href="https://www.nature.com/articles/s41598-018-23637-3.pdf" target="_blank" >https://www.nature.com/articles/s41598-018-23637-3.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-018-23637-3" target="_blank" >10.1038/s41598-018-23637-3</a>

Result language

angličtina

Original language name

Differences in cognitive functions between cytomegalovirus-infected and cytomegalovirus-free university students: a case control study

Original language description

Cytomegalovirus (CMV) is the herpetic virus, which infects 45-100% people worldwide. Many reports suggest that CMV could impair cognitive functions of infected subjects. Here we searched for indices of effects of CMV on infected subjects' intelligence and knowledge. The Intelligence Structure Test I-S-T 2000 R was used to compare IQ of 148 CMV-infected and 135 CMV-free university students. Infected students expressed higher intelligence. Paradoxically, their IQ decreased with decreasing concentration of anti-CMV antibodies, which can be used, statistically, as a proxy of the time passed from the moment of infection in young subjects when the age of subjects is statistically controlled. The paradox of seemingly higher intelligence of CMV infected subjects could be explained by the presence of the subpopulation of about 5-10% CMV-positive individuals in the population of "CMV-negative students". These false negative subjects had probably not only the oldest infections and therefore the lowest concentration of anamnestic antibodies, but also the lowest intelligence among the infected students. Prevalence of CMV infection in all countries is very high, approaching sometimes 90%. Therefore, the total impact of CMV on human intelligence may be large.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30303 - Infectious Diseases

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientific Reports

ISSN

2045-2322

e-ISSN

—

Volume of the periodical

8

Issue of the periodical within the volume

March

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

5322

UT code for WoS article

000428518900019

EID of the result in the Scopus database

2-s2.0-85044512170