Incidence and severity of pertussis hospitalisations in infants aged less than 1 year in 37 hospitals of six EU/EEA countries, results of PERTINENT sentinel pilot surveillance system, December 2015 to December 2018
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F21%3A00013403" target="_blank" >RIV/75010330:_____/21:00013403 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/21:00075868 RIV/00064211:_____/21:S0000004 RIV/00064203:_____/21:10425567 RIV/00216208:11130/21:10425567
Result on the web
<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.4.1900762" target="_blank" >https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.4.1900762</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2807/1560-7917.ES.2021.26.4.1900762" target="_blank" >10.2807/1560-7917.ES.2021.26.4.1900762</a>
Alternative languages
Result language
angličtina
Original language name
Incidence and severity of pertussis hospitalisations in infants aged less than 1 year in 37 hospitals of six EU/EEA countries, results of PERTINENT sentinel pilot surveillance system, December 2015 to December 2018
Original language description
Introduction: PERTINENT is a pilot active surveillance systaem of infants hospitalised with pertussis in six European Union/European Economic Area countries (37 hospitals, seven sites). Aim: This observational study aimed to estimate annual pertussis incidence per site from 2016 to 2018 and respective trends between 2017 and 2018. Pertussis cases were described, including their severity. Methods: We developed a generic protocol and laboratory guidelines to harmonise practices across sites. Cases were hospitalised infants testing positive for Bordetella pertussis by PCR or culture. Sites collected demographic, clinical, laboratory data, vaccination status, and risk/protective factors. We estimated sites' annual incidences by dividing case numbers by the catchment populations. Results: From December 2015 to December 2018, we identified 469 cases (247 males; 53%). The median age, birthweight and gestational age were 2.5 months (range: 0-11.6; interquartile range (IQR): 2.5), 3,280g (range: 700-4,925; IQR: 720 and 39 weeks (range: 25-42; IQR: 2), respectively. Thirty cases (6%) had atypical presentation either with cough or cyanosis only or with absence of pertussis-like symptoms. Of 330 cases with information, 83 (25%) were admitted to intensive care units including five deceased infants too young to be vaccinated. Incidence rate ratios between 2018 and 2017 were 1.43 in Czech Republic (p = 0.468), 0.25 in Catalonia (p = 0.002), 0.71 in France (p = 0.034), 0.14 in Ireland (p=0.002), 0.63 in Italy (p--= 0.053), 0.21 in Navarra (p = 0.148) and zero in Norway. Conclusions: Incidence appeared to decrease between 2017 and 2018 in all but one site. Enhanced surveillance of hospitalised pertussis in Europe is essential to monitor pertussis epidemiology and disease burden.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Euro Surveillance
ISSN
1025-496X
e-ISSN
1560-7917
Volume of the periodical
26
Issue of the periodical within the volume
4
Country of publishing house
SE - SWEDEN
Number of pages
12
Pages from-to
1900762
UT code for WoS article
000614121300001
EID of the result in the Scopus database
2-s2.0-85100597542