Changes in invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE Project
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F21%3A00013454" target="_blank" >RIV/75010330:_____/21:00013454 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/2076-2607/9/4/696" target="_blank" >https://www.mdpi.com/2076-2607/9/4/696</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/microorganisms9040696" target="_blank" >10.3390/microorganisms9040696</a>
Alternative languages
Result language
angličtina
Original language name
Changes in invasive pneumococcal disease caused by Streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE Project
Original language description
Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project gathered ST1 IPD surveillance data from sites globally and aimed to estimate PCV10/13 impact on ST1 IPD incidence. We estimated ST1 IPD incidence rate ratios (IRRs) comparing the pre-PCV10/13 period to each post-PCV10/13 year by site using a Bayesian multi-level, mixed-effects Poisson regression and all-site IRRs using a linear mixed-effects regression (N = 45 sites). Following PCV10/13 introduction, the incidence rate (IR) of ST1 IPD declined among all ages. After six years of PCV10/13 use, the all-site IRR was 0.05 (95% credibility interval 0.04-0.06) for all ages, 0.05 (0.04-0.05) for <5 years of age, 0.08 (0.06-0.09) for 5-17 years, 0.06 (0.05-0.08) for 18-49 years, 0.06 (0.05-0.07) for 50-64 years, and 0.05 (0.04-0.06) for >= 65 years. PCV10/13 use in infant immunization programs was followed by a 95% reduction in ST1 IPD in all ages after approximately 6 years. Limited data availability from the highest ST1 disease burden countries using a 3 + 0 schedule constrains generalizability and data from these settings are needed.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microorganisms
ISSN
2076-2607
e-ISSN
2076-2607
Volume of the periodical
9
Issue of the periodical within the volume
4
Country of publishing house
CH - SWITZERLAND
Number of pages
23
Pages from-to
696
UT code for WoS article
000643299400001
EID of the result in the Scopus database
2-s2.0-85103077847