Multi-country surveillance of paediatric invasive group A Streptococcus infection, European Union/European Economic Area countries, 2022/23 season
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F25%3A00015123" target="_blank" >RIV/75010330:_____/25:00015123 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/25:43928981
Result on the web
<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.42.2500079" target="_blank" >https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.42.2500079</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2807/1560-7917.ES.2025.30.42.2500079" target="_blank" >10.2807/1560-7917.ES.2025.30.42.2500079</a>
Alternative languages
Result language
angličtina
Original language name
Multi-country surveillance of paediatric invasive group A Streptococcus infection, European Union/European Economic Area countries, 2022/23 season
Original language description
Background: Group A Streptococcus (GAS) commonly causes mild bacterial infections but also deadly invasive disease. An upsurge in paediatric invasive GAS (iGAS) infections was observed during the last quarter of 2022 in the European Union/European Economic Area (EU/EEA) countries. Aim: We aimed to assess iGAS surveillance in the EU/EEA countries and investigate the epidemiology of iGAS infections during the 2022/23 season. Methods: We conducted a study on GAS and iGAS surveillance to evaluate coverage and surveillance methodology across the EU/ EEA countries. We collected and analysed data on paediatric iGAS cases (patients aged <= 16 years) occurring in September 2022-June 2023 that resulted in hospitalisation or death. Associations of severe outcome (admission to intensive care unit and/or death) with potential risk factors were estimated by logistic regression in a case-case analysis. Results: Nineteen countries responded to the questionnaire; eleven had mandated national surveillance for iGAS before 2022. Eight countries submitted data on 1,277 paediatric iGAS cases involving hospitalisation or death: 56% were males and median age was 4 years. Sixtythree (5%) of these cases died. Severe outcome was associated with emm1 type (odds ratio (OR) = 1.73; 95% confidence interval (CI): 1.13-2.67), having a sepsis without a known anatomic source (OR = 1.73; 95% CI: 1.11-2.73) and lower respiratory tract infections (OR = 4.14; 95% CI: 2.70-6.44). Conclusion: Surveillance of GAS and iGAS infections varied among the participating countries. We highlight the importance of including emm typing and analysis of clinical data in iGAS surveillance and having international collaboration for effective response to future surges.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Euro Surveillance
ISSN
1025-496X
e-ISSN
1560-7917
Volume of the periodical
30
Issue of the periodical within the volume
42
Country of publishing house
SE - SWEDEN
Number of pages
14
Pages from-to
2500079
UT code for WoS article
001613804600002
EID of the result in the Scopus database
2-s2.0-105019822701