Effect of age at exposure in 11 underground miners studies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652052%3A_____%2F14%3A%230000268" target="_blank" >RIV/86652052:_____/14:#0000268 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/rpd/ncu068" target="_blank" >http://dx.doi.org/10.1093/rpd/ncu068</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/rpd/ncu068" target="_blank" >10.1093/rpd/ncu068</a>

Result language
angličtina
Original language name
Effect of age at exposure in 11 underground miners studies
Original language description
Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
—

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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