Coping with iron limitation: a metabolomic study of Synechocystis sp PCC 6803

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652079%3A_____%2F18%3A00489000" target="_blank" >RIV/86652079:_____/18:00489000 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s11738-018-2603-1" target="_blank" >http://dx.doi.org/10.1007/s11738-018-2603-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11738-018-2603-1" target="_blank" >10.1007/s11738-018-2603-1</a>

Result language

angličtina

Original language name

Coping with iron limitation: a metabolomic study of Synechocystis sp PCC 6803

Original language description

Iron (Fe) is a key element for all living systems, especially for photosynthetic organisms because of its important role in the photosynthetic electron transport chain. Fe limitation in cyanobacteria leads to several physiological and morphological changes. However, the overall metabolic responses to Fe limitation are still poorly understood. In this study, we integrated elemental, stoichiometric, macromolecular, and metabolomic data to shed light on the responses of Synechocystis sp. PCC 6803, a non-N-2-fixing freshwater cyanobacterium, to Fe limitation. Compared to Synechocystis growing at nutrient replete conditions, Fe-limited cultures had lower growth rates and amounts of chlorophyll a, RNA, RNA: DNA, C, N, and P, and higher ratios of protein: RNA, C: N, C: P, and N: P, in accordance with the growth rate hypothesis which predicts faster growing organisms will have decreased biomass RNA contents and C: P and N: P ratios. Fe-limited Synechocystis had lower amounts Fe, Mn, and Mo, and higher amount of Cu. Several changes in amino acids of cultures growing under Fe limitation suggest nitrogen limitation. In addition, we found substantial increases in stress-related metabolites in Fe-limited cyanobacteria such antioxidants. This study represents an advance in understanding the stoichiometric, macromolecular, and metabolic strategies that cyanobacteria use to cope with Fe limitation. This information, moreover, may further understanding of changes in cyanobacterial functions under scenarios of Fe limitation in aquatic ecosystems.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10511 - Environmental sciences (social aspects to be 5.7)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Physiologiae Plantarum

ISSN

0137-5881

e-ISSN

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Volume of the periodical

40

Issue of the periodical within the volume

2

Country of publishing house

PL - POLAND

Number of pages

13

Pages from-to

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UT code for WoS article

000424497300007

EID of the result in the Scopus database

2-s2.0-85044352921