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Expression of inhibitors of cyclin-dependent kinases in leukemia.
Lower expression of p21 Cip cyclin-dependent kinase inhibitor may be a positive prognostic factor in acute myeloid leukemia....
FD - Onkologie a hematologie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Brain cyclin-dependent kinase 5 (Cdk5). I. Catalytic and activating subunits, selective syntetic inhibitors, and multimetric complexes.
Brain cyclin-dependent kinase 5 (Cdk5). I. Catalytic and activating subunits, selective syntetic inhibitors, and multimetric complexes....
FP - Ostatní lékařské obory
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Cyclin-dependent kinase inhibitors and cancer: usefulness of proteomic approaches in assesment of the molecular mechanisms and efficacy of novel therapeutics.
Cyclin-dependent kinase inhibitors and cancer: usefulness of proteomic approaches in assesmnet of the molecular mechanisms and efficacy of novel therapeutics....
FD - Onkologie a hematologie
- 2007 •
- C
Rok uplatnění
C - Kapitola v odborné knize
8-Azapurines as new inhibitors of cyclin-dependent kinases
CDK2, inhibitor, anticancer drug, 8- Azapurine...
FP - Ostatní lékařské obory
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Cyclin - dependent kinases inhibitor bohemine exhibits no embryotoxic effects
Bohemine and olomoucine are small-molecule inhibitors of cyclin-dependent kinases (CDKs) which have the ability to induce cell cycle arrest and apoptosis in a range of human tumor cells....
FE - Ostatní obory vnitřního lékařství
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
In vitro biotransformation of 2,6,9-trisubstituted purine-derived cyklin-dependent kinase inhibitor bohemine by mouse liver microsomes
Bohemine, tritium labelling, inhibition of cyklin-dependent kinase...
CE - Biochemie
- 2002 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Changes in expression of cyclins D1 and A1 and inhibitor of cyclin dependent kinases p21Cip signalise progression of CML.
Changes in expression of cyclins D1 and A1 correlate with BCR-ABL transcript level and disease status in patients with chronic myeloid leukemia. Elevated expression of inhibitor of cyclin-dependent kinases p21Cip signalise ...
FD - Onkologie a hematologie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture.
Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture......
EF - Botanika
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022)
Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of serine/threonine protein kinases and participates in the regulation of the cell cycle and mRNA transcription. CDK7 is emerging as a possible drug target in o...
Medicinal chemistry
- 2023 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases.
Inhibition of cyclin-dependent kinases (CDKs) has emerged as an attractive strategy for the development of novel oncol. therapeutics. Herein is described parameters to identify candidate CDK inhibitors with a suitable balan...
CC - Organická chemie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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