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miRBind: A Deep Learning Method for miRNA Binding Classification
The binding of microRNAs (miRNAs) to their target sites is a complex process binding is an important first step for any miRNA target prediction algorithm. To date, the potential for miRNA:target site
Genetics and heredity (medical genetics to be 3)
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Dicier: a Fine-tuned Bioinformatics Pipeline to Detect Micro-RNA Chimeric Reads
of potential miRNA binding sites. The Ago-miRNA regulatory function plays central roles of hybrid sequences between mRNA and its miRNA binding sites (chimeric sequences developed DICIER,...
Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
- 2019 •
- O •
- Link
Rok uplatnění
O - Ostatní výsledky
Výsledek na webu
MicroRNAs and Genetic Polymorphisms in Cancer
to predicted miRNA target sites within 3' UTR of mRNAs have the potential to affect the efficiency of miRNA binding on its target site, create or destroy binding sitesSingle nucleotide p...
FD - Onkologie a hematologie
- 2012 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer
Micro-RNAs (miRNAs) can bind to the 3' untranslated regions (UTRs) of messenger RNAs and interfere with their translation. Furthermore, miRNA regulation may be affected by polymorphisms on the 3' UTRs. We hypothesize that c...
EB - Genetika a molekulární biologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Genetic polymorphisms and MicroRNAs: new direction in molecular epidemiology of solid cancer
identified in predicted miRNA target sites within 3' untranslated regions of mRNAs. These SNPs have a potential to affect the efficiency of miRNA binding to the target sites or can create or disrupt b...
FP - Ostatní lékařské obory
- 2012 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Polymorphisms in miRNA-binding sites of nucleotide excision repair genes and colorectal cancer risk
the role of genetic variations in miRNA-binding sites of nucleotide excision repair located in miRNA-binding sites, with an in silico approach. Through the calculation of target DNA repair genes ...
EB - Genetika a molekulární biologie
- 2012 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB
-binding domain (dsRBD) pro-teins to convert precursor-microRNAs (pre-miRNAs Dicer-1 and its partner Loqs-PB cooperate (1) before binding pre-miRNA, (2) after reconstructions suggest that pre-miRNA bin...
Biochemistry and molecular biology
- 2022 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients
Polymorphisms in microRNA (miRNA) binding sites may affect miRNA/target gene hypothesized that genetic variations in miRNA binding sites located in mucin genes may study investigating miR...
Biochemistry and molecular biology
- 2017 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer
explored. SNPs in genes encoding the miRNA sequence or in 3'UTR regions of the corresponding binding sites may affect miRNA transcription, miRNA processing, and/or the fi delity of the miRNA-mRNA...
EB - Genetika a molekulární biologie
- 2016 •
- C •
- Link
Rok uplatnění
C - Kapitola v odborné knize
Výsledek na webu
miRNAsong: a web-based tool for generation and testing of miRNA sponge constructs in silico
MicroRNA (miRNA) sponges are RNA transcripts containing multiple high-affinity binding sites that associate with and sequester specific miRNAs to prevent them from interacting with their target messenger (m) RNAs. ...
CE - Biochemie
- 2016 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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