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Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
Background: Interleukin (IL)-20 is a pro-inflammatory cytokine that may to determine the association between IL-20 and disease activity in patients with RA. Methods: The levels of serum and synovial fluid IL-20 wer...
Rheumatology
- 2017 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Risankizumab (Skyrizi)
treatment methods over the past 20 years. Identification of the essential role of interleukin 23 (IL-23) as the main regulatory cytokine and confirmation of the importance of interleukin 23/Th lymphocytes 17 (IL-23/Th17) p...
Dermatology and venereal diseases
- 2019 •
- Jost •
- Link
Rok uplatnění
Jost - Ostatní články v recenzovaných periodicích
Výsledek na webu
Severe acute pancreatitis - laboratory monitoring aimed to discriminate sterile and infected neckrosis
Objective: Our retrospective study aimed to evaluate the contribution of interleukin-6 in severe acute pancreatitis. Mortality of severe acute pancreatitis ranges from 10-20% (for sterile necrosis, SN) to 20-85% (infected n...
FE - Ostatní obory vnitřního lékařství
- 2012 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Production of interleukin 1beta and interferon gamma by bovine mammary gland leukocytes stimulated by lipopolysaccharide
The aim of this trial was to investigate the production of the pro-inflammatory cytokines interleukin 1beta (IL-1β) and interferon gamma (IFN-γ) produced by bovine mammary gland leukocytes following lipopolysaccharide (LPS) challenge (5 μg L...
Animal and dairy science; (Animal biotechnology to be 4.4)
- 2018 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Dupilumab Therapy in a Patient with Atopic Dermatitis and Severe Atopic Keratoconjunctivitis
Atopic dermatitis is an inflammatory skin condition affecting 1 to 20% of the population worldwide. Ocular comorbidities like conjunctivitis, keratitis and keratoconus have been more often described in atopic patients. Aproximately 20
Dermatology and venereal diseases
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Efficacy and Safety of Anti-Interleukin-20 Monoclonal Antibody in Patients With Rheumatoid Arthritis A Randomized Phase IIa Trial
Objective. Interleukin-20 (IL-20) is implicated in the pathogenesis of rheumatoid arthritis (RA). The efficacy, safety, and tolerability of NNC0109-0012, a selective anti-IL-20 recombinant human monoclonal antibody...
FP - Ostatní lékařské obory
- 2015 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Alcoholism and interleukin 6
alcoholism, interleukin 6...
FL - Psychiatrie, sexuologie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer
Serum interleukin (IL)-6 levels correlate with disease outcomes in renal cell carcinoma (RCC) patients. Siltuximab, a chimeric, murine-human mAb against IL-6 x 4; in part 3, 20 low-risk patients received 6 mg kg(-1) q2w x 6. Modifie...
FD - Onkologie a hematologie
- 2010 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Intracellular Interleukin 1-alpha Functionally Interacts with Histone Acetyltransferase Complexes
Function of nuclear interleukin-1alpha...
EB - Genetika a molekulární biologie
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Topical duodenal and gastric mucosal production of interleukin-1beta, interleukin-6, interleukin-8, tumour necrosis alpha and interleukin-2-soluble receptor in Helicobacter pylori positive
Pathogenesis of Helicobacter pylori (Hp) gastritis and duodenitis has not been fully explained yet. Aim of this project was to study topical duodenal and gastric cytokine production by means of ex-vivo in-vitro culture. A total number of 85 biopsy sp...
FE - Ostatní obory vnitřního lékařství
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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