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Genes coding for acetyhydroxy acid synthase in Streptomyces cinnamonensis and their regulatory region:Mutations in the catalytic subunit conferring insesitivity to end-product inhibition
increased monensin A production. Gene ilvB coding for the AHAS catalytic subunit resulting in the deletion of Q217. A homology model of the catalytic subunit, created by a virtue of the known three-dimens...
EE - Mikrobiologie, virologie
- 2004 •
- D
Rok uplatnění
D - Stať ve sborníku
Deregulation of acetohydroxy-acid synthase: loss of allosteric inhibition conferred by mutations in the catalytic subunit
The ilvB genes coding for acetohydroxy acid synthase (AHAS) catalytic subunit from the Streptomyces cinnamonensis parental strain and four mutants deregulated revealed that the substitution E139A is located in a loop at the...
EE - Mikrobiologie, virologie
- 2008 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c
Silencing in HEK293 cell line by RNAi of ATP5E gene encoding the epsilon subunit resulted in inhibition of biogenesis of ATP synthase and accumulation of hydrophobic subunit c of the rotor structure of the enzyme. Results i...
EB - Genetika a molekulární biologie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Subunit?subunit interactions are weakened in mutant forms of acetohydroxy acid synthase insensitive to valine inhibition
in valine regulation, the impact of mutations on interactions between the catalytic and the regulatory subunits was examined using yeast twohybrid system. Mutations in the catalytic changes in the catalytic su...
EE - Mikrobiologie, virologie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
ATP synthase from trypanosoma brucei has an elaborated canonical f1-domain and conventional catalytic sites
those subunits involved directly in the catalytic formation of ATP, are widely a noncanonical structure and different catalytic sites in which the catalytically essential arginine finger is provided not by the α-<...
Medical biotechnology related ethics
- 2018 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
The using of telomerase catalytic subunit as tumor antigen in multiple myeloma
The using of telomerase catalytic subunit as tumor antigen in multiple myeloma was presented...
EC - Imunologie
- 2005 •
- O
Rok uplatnění
O - Ostatní výsledky
Composition and Function of Telomerase-A Polymerase Associated with the Origin of Eukaryotes
a reverse transcription mechanism. Both core subunits of telomerase-its catalytic telomerase reverse transcriptase (TERT) subunit and telomerase RNA (TR) component-were telomerase subunits have been described in v...
Biochemistry and molecular biology
- 2020 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
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Rescue of a telomere length defect of Nijmegen Breakage Syndrome cells requires NBS and telomerase catalytic subunit.
Rescue of a telomere length defect of Nijmegen Breakage Syndrome cells requires NBS and telomerase catalytic subunit were described. , , ,......
FD - Onkologie a hematologie
- 2001 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Phosphorylation of Type IA restriction-modification complex enzyme EcoKI on the HsdR subunit
strainsharbouring the corresponding hsd genes, and in vitro by phosphorylation assay using-modification enzymes, the HsdR subunit of EcoKI system was the only subunit, whichwas-produced with HsdM and HsdS subunits...
EE - Mikrobiologie, virologie
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction
Telomere repeats are added onto chromosome ends by telomerase, consisting of two main core components: a catalytic protein subunit (telomerase reverse trancriptase, TERT), and an RNA subunit (telomerase RNA, TR). The abilit...
EB - Genetika a molekulární biologie
- 2012 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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