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Bone cement as a cytostatic drug carrier - possibilities of use, experiments in vitro
Using the bone cement as a carrier of methotrexate is a possibility of secondary bone tumours local treatment. this method recovers biomechanical properties of bone and provides local chemotherapeutic effect. The aim of the present project w...
FI - Traumatologie a ortopedie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Cytostatic and immunomobilizint activities of polymer-bound drugs.
One of the new approaches in the treatment of cancer is affinity therapy based on synthetic polymeric carriers.
EE - Mikrobiologie, virologie
- 2003 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Anticancer Therapy Using Biodegradable Hydrogels-Combined With Antibody-Targeted Conjugates or Surgery: Insights Into The In Vivo Action.
HPMA copolymer has been developed as a carrier of cytostatic drugs.
EE - Mikrobiologie, virologie
- 2003 •
- D
Rok uplatnění
D - Stať ve sborníku
HPMA copolymer-drug conjugates with controlled tumor-specific drug release
-soluble polymer carriers of low-molecular-weight drugs and compounds, e.g., cytostatic agents, anti-inflammatory drugs, or multidrug resistance inhibitors, all covalentlyOver the past few decades, numerous polymer...
Polymer science
- 2018 •
- Jimp •
- Link
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Coordination conjugates of therapeutic proteins with drug carriers: A new approach for versatile advanced drug delivery
We present here a general system for the coordination attachment of therapeutic proteins to a drug delivery system and its application in combined therapy. Proof of concept is demonstrated by the synthesis and testing of the targeted dru...
CE - Biochemie
- 2011 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
HPMA-based polymer conjugates with drug combination
Synthesis and physico-chemical behavior of new polymer?drug conjugates intended for the treatment of cancer were investigated. In the polymer conjugate with the expected dual therapeutic activity, two drugs, a cytostatic ag...
CD - Makromolekulární chemie
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through and amide or hydrazone bond
The cytostatic effects of polymeric conjugates based on N-(2-hydroxypropyl)methacrylamide copolymers (PHPMA) and containing doxorubicin bound through amide and hydrazone bonds (mixed conjugates) were compared with the cytostatic eff...
EC - Imunologie
- 2010 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Star like polymer nanotherapeutics based on biodegradable dendritic core and hydrophilic polymer tailored for high uptake in solid tumors
highly hydrophobic drugs. The cytostatic drug doxorubicin is covalently bound. After delivery of the drug to the tumor tissue, the polymeric carrier returnsThe star-like water-soluble polymeric carrie...
Polymer science
- 2020 •
- Gfunk
Rok uplatnění
Gfunk - Funkční vzorek
Cytostatic and immunomobilizing activities of polymer-bound drugs
Polymer-bound, doxorubicin, cytostatic...
EC - Imunologie
- 2002 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Poly(ethylene glycol)-based polymer carrier of doxorubicin degradable by both enzymatic and chemical hydrolyses
A new multivalent multiblock PEG-based polymer suitable for modification of biologically active compounds was synthesized and charactyerized. Biological evaluation of this new biodegradable polymer as a carrier of cytostatics and as...
CD - Makromolekulární chemie
- 2005 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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