All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Filters

24 (0,069s)

Result

Canagliflozin

Canagliflozin is a highly selective inhibitor of the sodium-glucose inhibition with canagliflozin increases glucose excretion by the kidneys, resulting. Canagliflozin is currently approved for the treatment of type 2 diabet...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2014
  • Jx
Result

Canagliflozin

Canagliflozin is an oral antidiabetic drug from the classof sodium-glucose of canagliflozin in monotherapyor in combination with other antidiabetics in patients a beneficial effectof canagliflozin on the incidence of major ...

Endocrinology and metabolism (including diabetes, hormones)

  • 2023
  • Jost
  • Link
Result

Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes

Aims: To assess the efficacy and safety of canagliflozin, a sodium glucose co in the CANagliflozin cardioVascular Assessment Study (CANVAS) who were on an incretin mimetic participants to canagliflozin 100 or 300 mg or plac...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2016
  • Jx
  • Link
Result

Canagliflozin and its position in the treatment of type 2 diabetes

Canagliflozin is an inhibitor of sodium-glucose cotransporter 2 (SGLT2 inhibitors, dose titration from 100 mg to 300 mg is possible with canagliflozin the mechanism of action of canagliflozin and its pharmacokinetics and dr...

Endocrinology and metabolism (including diabetes, hormones)

  • 2024
  • Jost
  • Link
Result

Canagliflozin: clinical significance of simultaneous balanced influencing of SGLT2 and SGLT1

Gliflozins - or SGLT2 inhibitors - interfere with renal glucose reabsorption by inhibiting glucose transporters SGLT2. As a result, they cause glucosuria, glycemia lowering, loss of energy with weight reduction, and improvement of diabetes compensati...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015
  • Jx
Result

Fixed dose combination of canagliflozin and metformin

The fixed-dose combination canagliflozin/metformin is indicated in patients with type 2 diabetes as adjuvant therapy together with diet and exercise regimen, provided the disease cannot be controlled with monotherapy. Canagliflozin,...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015
  • Jx
Result

CANVAS – Canagliflozin and cardiovascular or renal influence for diabetes mellitus type 2

Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that reduces glycaemia as well as blood pressure, body weight, and albuminuria in people in each trial were randomly assigned to receive canagliflozin or placebo and were o...

General and internal medicine

  • 2019
  • JSC
  • Link
Result

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

BACKGROUND Canagliflozin is a sodium-glucose cotransporter 2 inhibitor with diabetes. We report the effects of treatment with canagliflozin on cardiovascular canagliflozin or placebo and were followed for a mean of 188.2 we...

Endocrinology and metabolism (including diabetes, hormones)

  • 2017
  • Jimp
  • Link
Result

Alternative method for canagliflozin oxidation analysis using an electrochemical flow cell - Comparative study

-stress testing of active pharmaceutical ingredients using canagliflozin as a model of canagliflozin, and the percentage of the corresponding peak areas. Our results showed of canagliflozin, namely 50 µm cell size, 300 mM e...

Analytical chemistry

  • 2022
  • Jimp
  • Link
Result

Canagliflozin-loaded magnetic nanoparticles as potential treatment of hypoxic tumors in combination with radiotherapy

Aim: To synthesize magnetic nanoparticles loaded with the SGLT2-inhibitor canagliflozin (CANA) and evaluate its anticancer potential under normoxic and hypoxic conditions in combination or not with radiotherapy. Material & methods: Iron ...

Physical chemistry

  • 2018
  • Jimp
  • Link
  • 1 - 10 out of 24