All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Filters

85 (0,101s)

Result

Prolyl Oligopeptidase in Physiology and Pathology

Prolyl oligopeptidase is an atypical serine peptidase which digests bioactive peptides, including hormones and neuropeptides. Prolyl oligopeptidase cleaves internal peptide bonds on the C-terminal side of proline r...

Biochemistry and molecular biology

  • 2019
  • Jimp
  • Link
Result

Alkaloids from Chlidanthus fragrans and their acetylcholinesterase, butyrylcholinesterase and prolyl oligopeptidase activities

butyrylcholinesterase inhibition activity using Ellman's method. In the prolyl oligopeptidase assay and prolyl oligopeptidase inhibition activity. Other isolated compounds were considered......

FR - Farmakologie a lékárnická chemie

  • 2013
  • Jx
Result

Isoquinoline alkaloids as prolyl oligopeptidase inhibitors

Prolyl oligopeptidase is a cytosolic serine peptidase that hydrolyses proline-containing peptides at the carboxy terminus of proline residues. It has been associated with schizophrenia, bipolar affective disorder, and related neurop...

FR - Farmakologie a lékárnická chemie

  • 2015
  • Jx
  • Link
Result

Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors

Prolyl oligopeptidase (POP), also called prolyl endopeptidase, is a cytosolic enzyme investigated by several research groups. It has been proposed to play an important role in physiological processes such as modulation of t...

Pharmacology and pharmacy

  • 2017
  • Jimp
  • Link
Result

Cholinesterase and prolyl oligopeptidase inhibitory activities of alkaloids from Argemone platyceras (Papaveraceae)

of acetylcholinesterase, butyrylcholinesterase, and prolyl oligopeptidase can be beneficial targets prolyl oligopeptidase inhibitory activity. The alkaloids inhibited the enzymes, inhibited both acetylcholinestera...

Biochemistry and molecular biology

  • 2017
  • Jimp
  • Link
Result

Alkaloids from Peumus boldus and their Acetylcholinesterase, Butyrylcholinesterase and Prolyl Oligopeptidase Inhibition Activity

. In the prolyl oligopeptidase assay, Z-Gly-Pro-p-nitroanilide was used as substrate +/- 3.0 mu M and 15.0 +/- 1.4 mu M, respectively. Important prolyl oligopeptidase......

FR - Farmakologie a lékárnická chemie

  • 2015
  • Jx
Result

Alkaloids from Peumus boldus and their Acetylcholinesterase, Butyrylcholinesterase and Prolyl Oligopeptidase Inhibition Activity

. In the prolyl oligopeptidase assay, Z-Gly-Pro-p-nitroanilide was used as substrate +/- 3.0 mu M and 15.0 +/- 1.4 mu M, respectively. Important prolyl oligopeptidase......

Electrical engineering, Electronic engineering, Information engineering

  • 2015
  • Jimp
  • Link
Result

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors

is focusedon Schistosoma mansoni prolyl oligopeptidase (SmPOP) from the serine peptidase oligopeptidase that hydrolyzes peptide (but not protein) substrates with a strict specificity......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2015
  • Jx
  • Link
Result

Isoquinoline Alkaloids from Fumaria officinalis L. and Their Biological Activities Related to Alzheimer's Disease

for their acetylcholinesterase, butyrylcholinesterase, prolyl oligopeptidase (POP), and glycogen synthase...

CB - Analytická chemie, separace

  • 2016
  • Jx
  • Link
Result

Revised NMR Data for 9-O-Demethylgalanthine: an Alkaloid from Zephyranthes robusta (Amaryllidaceae) and its Biological Activity

in acetylcholinesterase/butyrylcholinesterase assays (IC50> 500 mu M), but showed important prolyl oligopeptidase inhibition activity....

CC - Organická chemie

  • 2014
  • Jx
  • Link
  • 1 - 10 out of 85