All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Filters

11 188 (0,087s)

Result

A simple approach for fabrication of optical affinity-based bioanalytical microsystem on polymeric PEN foils

available for localized covalent immobilization of biotin. High affinity binding protein(albumin-binding domain (ABD) of protein G, Streptococcus G148) recognizing human serum albumin(HSA), genetically fused with ...

Materials engineering

  • 2018
  • Jimp
  • Link
Result

The location of the high- and low-affinity bilirubin-binding sites on serum albumin: Ligand-competition analysis investigated by circular dichroism

The locations of three bilirubin (BR)-binding sites with different affinities were identified as subdomains IB, IIA and IIIA for five mammalian serum albumins). The stereoselectivity of a high-affinity BR-binding s...

CB - Analytická chemie, separace

  • 2013
  • Jx
  • Link
Result

Study on the interactions of sulfonylurea antidiabetic drugs with normal and glycated human serum albumin by capillary electrophoresis-frontal analysisis

the affinities between human serum albumin or its glycated form and the first generation human serum albumins, with glycated giving lower values....

CE - Biochemie

  • 2016
  • Jx
  • Link
Result

Antioxidants and environmental stress: Effect of low-molecular compounds on molecule of protein

The aim of the study was to evaluate the relationships between the chemical structure of tea catechins and their binding affinities to serum albumin by fluorescence quenching method. The quenching constants, binding constan...

DN - Vliv životního prostředí na zdraví

  • 2010
  • D
Result

Determination of binding constant of 1st generation antidiabetic drug with human serum albumin

The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between selected 1st generation antidiabetic drugs (tolbutamide, chlorpropamide) and human serum albumin (HSA). The binding constant (Kb...

CE - Biochemie

  • 2014
  • D
Result

Albumin and alfa1-acid glycoprotein: old acquaintances

Albumin and alfa1-acid glycoprotein (AGP) are two of the most abundant proteins found in plasma. Their effect on the pharmacokinetic profile of exogenous compounds has major implications to clinical practice. Recent exploration into their po...

FR - Farmakologie a lékárnická chemie

  • 2013
  • Jx
  • Link
Result

Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis

The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between diclofenac and tryptophan, and human serum albumin (HSA). Apparent log Kb = (4.4 ? 0.01) L/mol for diclofenac?HSA and log Kb = (...

CE - Biochemie

  • 2014
  • D
Result

The effects of heme-binding proteins on the peroxidative and catalatic activities of hemin.

The plasma proteins hemopexin (Hx) and albumin (Alb) are known to bind heme with high and medium affinity, respectively. To study how this binding modifies heme catalytic reactivity, the effects of Hx, human serum Alb (HSA)...

FD - Onkologie a hematologie

  • 1999
  • Jx
Result

Serum albumin as a primary non-covalent binding protein for nitro-oleic acid

serum albumin (HSA). The molecular mechanism of the biological action of NO2-OA with significantly higher affinity. NO2-OA competes with ibuprofen for FA-3 and FA-6, however, in contrast to the situation with warfarin, the...

Biochemistry and molecular biology

  • 2022
  • Jimp
  • Link
Result

Albumin and alpha 1-acid glycoprotein: old acquaintances

Albumin and alpha 1-acid glycoprotein (AGP) are two of the most abundant proteins found in plasma. Their effect on the pharmacokinetic profile of exogenous compounds has major implications to clinical practice. Recent exploration into their ...

FR - Farmakologie a lékárnická chemie

  • 2013
  • Jx
  • Link
  • 1 - 10 out of 11 188