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34 780 (0,107s) •

Result

Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring

Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring......

FD - Onkologie a hematologie

  • 2006
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  • Jx
Result

Mutations in the Wilms' tumor 1 gene cause isolated steroid resistant nephrotic syndrome and occur in exons 8 and 9

Primary steroid-resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end-stage renal disease. Approximately 10-25% of familial and sporadic cases are caused by mutations in NPHS2 (podocin). Mutatio...

FG - Pediatrie

  • 2006
    • •
  • Jx
Result

Bromodomain 4 inhibition leads to MYCN downregulation in Wilms tumor

Background Wilms tumor is the most common childhood kidney cancer. Two distinct histological subtypes of Wilms tumor have been described: tumors lacking anaplasia with a number of pediatric cancers includi...

Oncology

  • 2022
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  • Jimp
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  • Link
Result

Mulibrey Nanism and Wilms Tumor

Mulibrey Nanism and Wilms Tumor...

EB - Genetika a molekulární biologie

  • 1999
    • •
  • Jx
Result

Wilms tumor gene 1 (WT1), TP53, RAS/BRAF and KIT aberrations in testicular germ cell tumors

Purpose: Wilms tumor gene 1 (WT1), a zinc-finger transcription factor essential for testis development and function, along with other genes, was investigated for their role in the pathogenesis of testicular germ ce...

FD - Onkologie a hematologie

  • 2016
    • •
  • Jx
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  • Link
Result

Adult Wilm's tumor - a rare case

We present a case report of a 39 year-old patient who underwent a partial nephrectomy because of tumor. Histopathology resultsrevealed a rare case of adult Wilms' tumor. Patient underwent an adjuvant chemotherapy and i...

Oncology

  • 2017
    • •
  • Jost
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  • Link
Result

Real-time PCR quantification of major Wilms' tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences

Wilms' tumor gene 1 (WT1) functions including some contradictory effects may be explained by the presence and interactions of its isoforms, however, their evaluation has been so far complicated by several technical problems...

FD - Onkologie a hematologie

  • 2012
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  • Jx
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  • Link
Result

Evaluation of WT1 expression in bone marrow vs peripheral blood samples of children with acute myeloid leukemia-impact on minimal residual disease detection

Wilms' tumor gene 1 (WT1) is located on chromosome 11p13. As a zinc finger transcription factor, WT1 regulates expression of many target genes involved in regulation of cell cycle, proliferation, differentiation an...

FD - Onkologie a hematologie

  • 2013
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  • Jx
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  • Link
Result

Allele loss in wilms tumors of chromosome arms

EB - Genetika a molekulární biologie

  • 1998
    • •
  • Jx
Result

Nephroblastoma - current evaluation and treatment

Nephroblastoma (Wilms tumor - WT) is the most common solid renal tumor in children. The patients are treated according to SIOP 2001 protocol. This protocol recommends pre-operative chemotherapy, nephrectomy and postoperativ...

FD - Onkologie a hematologie

  • 2016
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  • Jx
    • •
  • Link
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