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Short half-life of IL-2 in circulation can be dramatically prolonged by forming of biologically active IL-2 immunocomplexes
In this study we tried short half-life of IL-2 in circulation can be dramatically prolonged by forming of biologically active IL-2 immunocomplexes......
EC - Imunologie
- 2009 •
- O
Rok uplatnění
O - Ostatní výsledky
Borna disease virus (BDV) circulating immunocomplex positivity in addicted patients in the Czech Republic: a prospective cohort study
BDV is a RNA neurotropic virus, causes mood and behaviour changes, infection is associated with psychiatric disorders. We examined BDV CIC seropositivity in 41 addicted patients and healthy individuals....
FL - Psychiatrie, sexuologie
- 2010 •
- A
Rok uplatnění
A - Audiovizuální tvorba
Circulating immunocomplexes in the serum of patients with lupus erythematosus and its subtypes prior to and after treatment
FP - Ostatní lékařské obory
- 1994 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
IL-2 immunocomplexes ? novel approach in cancer treatment and modulation of immune responses
The purpose of this study was to evaliate the immunomodulating potential of two IL-2 immunocomplexes formed by IL-2 and anti-IL-2 mAbs, namely S4B6 and JES6-1, which were recently described to have strong in vivo stimulatory activity toward ...
EE - Mikrobiologie, virologie
- 2010 •
- O
Rok uplatnění
O - Ostatní výsledky
Antitumor activity of IL-2/anti-IL-2 mAb immunocomplexes exerts synergism with that of N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugate due to its low immunosuppressive
drawbacks. It has been shown that immunocomplexes of IL-2 and certain anti-IL-2 mAbs mAb immunocomplexes expand not only CD122high subsets and newly activated CD81 T that natural killer (NK) cells expanded by IL-2/S4B6 mAb immu...
EC - Imunologie
- 2011 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Robust in vivo expansion of activated naive CD8+ T cells and NK cells by IL-2 immunocomplexes
It was demonstrated recently tahm immunocomplexes of IL-2 nad anti-IL-2 mAb possess strong biological activity in vivo and selectively stimulates differen population....
EC - Imunologie
- 2009 •
- O
Rok uplatnění
O - Ostatní výsledky
IL-2/anti-IL-2 mAb immunocomplexes: A renascence of IL-2 in cancer immunotherapy?
he in vivo biological activity of IL-2 can be dramatically increased by complexing with anti-IL-2 mAb. Moreover, IL-2/anti-IL-2 mAb immunocomplexes selectively. Conversely, IL-2/JES6.1 mAb immunocomplexes have no stimulatory activit...
EE - Mikrobiologie, virologie
- 2016 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Chimera of IL-2 Linked to Light Chain of anti-IL-2 mAb Mimics IL-2/anti-IL-2 mAb Complexes Both Structurally and Functionally
IL-2/anti-IL-2 mAb immunocomplexes were described to have dramatically higher).This protein chimera mimics the structure of IL-2/S4B6 mAb immunocomplexes but eliminates general disadvantages of immunocomplexes like possible...
CE - Biochemie
- 2013 •
- Jx •
- Link
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
About the afinity interaction of biosensors and precision of teh dynamical frequency response measurement.
The paper deals with the formation of immunocomplex ASC at the surface of the AT-cut quartz resonator vibrating in thickness-shear mode. The biochemical affinity process can be characterized by association ka and dissociation kd kinetic rate...
BM - Fyzika pevných látek a magnetismus
- 2003 •
- D
Rok uplatnění
D - Stať ve sborníku
Immunological Indicators in Dogs Affected by Deep Pyoderma
lymphocytes. Lower values of circulating immune complexes in affected dogs were...
GJ - Choroby a škůdci zvířat, veterinární medicina
- 2007 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
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